Predicting directional flexibility in proteins

BackFlip-2 predicts directional protein backbone flexibility and dynamic correlations directly from structures via a fast SE(3)-equivariant graph neural network, matching larger ensemble models at orders-of-magnitude lower cost.

Vsevolod Viliuga, Leif Seute, Matteo Tadiello, Nicolas Wolf and 2 more

Paris Poster Session 6, Fri, Dec 11, 2:30 PM–4:30 PM, Paris Poster Hall · Published 2026