Good Papers

JEPA-Anything: Learning Predictive Models across Different Worlds

JEPA-Anything uses orthogonal predictive factorization to learn cross-domain predictive models that outperform baselines in vision, biology, clinical, control, molecular, physical, and weather domains.

Taoyong Cui, Zhongyao Wang, Xinyue Xu, Weiyang Liu, Zhaochen Yu, Yuying Zhang, Qiang Gao, Mengyue Yang, Wanli Ouyang, Pheng Ann Heng, Yingcheng Wu, Zhenfei Yin, Ling Yang

Published Sep 17, 2026▲ 77 on Hugging FaceCode ★ 261arXiv ↗

86%
OverallMust read
?
OverallMust readVote to see the scoreThe exact score shows once you've voted, so every vote is your own call. The first half of each home page shelf shows its scores.
Readers
–

Only vote on papers you've read. Sign in with GitHub to vote.

AI panel14/20reviewers recommend it
lenient 5/5
medium 7/10
strict 2/5
AI panel?Vote to see what the 20 AI reviewers said
Panel consensus
JEPA-Anything delivers a concrete orthogonal predictive factorization with rare experimental validation across seven domains and a 34.8% dynamics gain, though its cross-domain common-principle claim is undermined by missing standardized baselines and an unproven cross-transfer test beyond…

Abstract

World modeling enables intelligence to anticipate consequences, guide interventions, and learn from interaction. Yet predictive models remain domain-specific: can a common learning principle support world modeling across radically different systems? We introduce JEPA-Anything, a domain-agnostic framework based on orthogonal predictive factorization (OPF). Extending joint-embedding predictive architectures, OPF decomposes latent targets into complementary factors, learns them through dedicated pathways, and recombines them within a shared predictive design. We evaluate JEPA-Anything across seven domains: vision, biology, clinical trajectories, control, molecular dynamics, physical fields, and weather. Experiments span representation learning, intervention prediction, out-of-distribution generalization, and long-horizon dynamics, including 10 matched dynamics tasks, forecasting of over 1,000 clinical events, and 100-step molecular rollouts across four systems. Against matched JEPA baselines, JEPA-Anything improves reported metrics on all 10 dynamics tasks and reduces single-intervention prediction error on Interventional Pong by 34.8%. It achieves the lowest one-step and 100-step molecular errors among compared methods in all four systems. Beyond prediction, a factor-nominated biological intervention receives experimental support in cell co-cultures, patient-derived organoids, tumor fragments, and mice; latent orbital modes recover the Keplerian scaling exponent with a fitted slope of -1.4991. These results support a common factorized predictive principle across heterogeneous worlds, connecting world modeling with intervention and experimentally grounded scientific discovery. Code: https://github.com/Gen-Verse/JEPA-Anything