[Hormonal changes in open-angle glaucoma. II. Levels of cortisol and somatotropin in serum].
Serum cortisol and growth hormone elevation occurred in about 40% and 9% of open-angle glaucoma patients, respectively, with growth hormone increases nearly always coinciding with abnormal insulin curves, implicating hormonal dysregulation in both diabetes and glaucoma onset.
Published 19931 citationPaper ↗
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Abstract
Observing interrelation between carbohydrate metabolism disorders and contrainsular mechanisms in a group of 102 glaucomatous patients, a higher level of cortisol in plasma was detected in 40.2% of glaucomatous patients of whom 31% had increased levels of cortisol together with IRI. In isolation the increased level of cortisol occurred in 8.9%. The frequency of increased cortisol level in glaucomatous patients is substantially lower (40.2%) than the frequency of abnormal insulin curves (78%). Increased levels of growth hormone in the group of patients occurred in 9.3% of cases and these were almost always associated with an abnormal immuno-reactive insulin curve (IRI curve). Accordingly, it is evident that hormonal disorders are a major factor in the onset of both diabetes and glaucoma.