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Abstract 7600: Synergy of ZEN3694 and VIP152 for dual transcriptional targeting of BET and CDK9 in patient derived organoid models of pancreatic cancer

Combined BET inhibitor ZEN3694 and CDK9 inhibitor VIP152 synergistically kill pancreatic cancer organoids by suppressing RNA polymerase II phosphorylation and antiapoptotic proteins.

Lucas J. Koeppel, Austin Stram, Robert J. Millikin, Ellie Riedl and 4 more

Published Mar 22, 2024 · 0 citations

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